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Auranofin The antiarthritic gold(I) phosphine compound [(2,3,4,6-tetra-O-acetyl-1-(thio-κS)-β-D-glucopyranosato)(triethyl-phosphine)gold(I)], auranofin (AUF), was introduced clinically as an oral antiarthritic in 1979 (Figure 8C) [176]