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Immunosenescence is the progressive decline of the immune system with age, primarily due to the involution of the thymus—the organ that matures T lymphocytes

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The cultured SGNs from P3 WT mice were incubated with 100 μM peroxynitrite for 48 h with or without the pretreatment of 30 μM ebselen for 1 h, or the SGNs from gpx1 –/– mice were cultured and exposed to 100 μM peroxynitrite for 48 h