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agent → model), there are prostaglandins analogues—ethanol model (Robert, 1979) relationships, NSAIDs—acetic acid model (Okabe and Amagase, 2005) relationships, dopamine agonists—cysteamine model (Selye and Szabo, 1973) relationships, and H 2 blockers—cysteamine model (Selye and Szabo, 1973) relationships

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In many other areas, oral substitution at a sufficiently high dosage has already proven to be equivalent to injections and an improvement of neurological symptoms seems to be equally possible through oral administration (45, 46)