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“In practice, [hydroquinone] compounded up to 8% is considered to be high and is only recommended for short periods of time,” says Lesley Clark-Loeser, MD, a board-certified dermatologist in Davie, Florida

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The peptide has also been connected to activation of the FAK-paxillin signaling pathway, which governs endothelial cell migration — a necessary step in angiogenic processes — as well as modulation of nitric oxide signaling and cytoprotective cascades