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146 Sapidolide A, extracted from a folk medicine used in China to treat inflammatory diseases, inhibits expression and activation of the NLRP3 inflammasome when used as a pretreatment in a mouse model of APAP-induced liver injury

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As FDA summarized during its presentation: “We can’t create quality standards unless we actually know what it is.” FDA's position is that a prescriber, pharmacy, API manufacturer, and testing laboratory must all be referring to the same substance